DNA-binding Diruthenium Complex

Bis-dipyridophenazine into DNA double helix

Thread insertion of a Bis(dipyridophenazine) diruthenium complex into the DNA double helix by the extrusion of AT base pairs  and cross-linking of DNA duplexes (2014)

Angew Chem Int Ed Engl.53, 1949-1952.

Three-Way Junction

Three way DNA junction

Molecular recognition of a three-way DNA junction by a metallosupramolecular helicate (2006)

Angew Chem Int Ed Engl.45(8), 1227-31.

Holliday Junction

DNA Holliday junction

Crystal structure of a DNA Holliday junction (1999)

Nature Structural Biology 6, 913 – 917.

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